Trials Currently Enrolling
NTM MAC Clinical Trials – Mild Disease
- Hypertonic Saline for Treatment of Pulmonary Mycobacterium Avium Complex (MAC) Disease
- Clofazimine in the treatment of pulmonary Mycobacterium avium complex disease – More information available at the OHSU Research Participation Opportunity website
- A Randomized, Double-Blinded, Placebo-Controlled, Multicenter, Phase 2, Dose-Ranging Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SPR720 as Compared with Placebo for the Treatment of Patients with Mycobacterium avium Complex (MAC) Pulmonary Disease
NTM MAC Clinical Trials – Mild to Moderate Disease
- Comparison of two- versus three-antibiotic therapy for pulmonary Mycobacterium avium complex disease – More information available on the MAC 2v3 website
- ENCORE – A Randomized, Double-Blind, Placebo-Controlled, Active Comparator, Multicenter Study to Evaluate the Efficacy and Safety of an Amikacin Liposome Inhalation Suspension (ALIS)-Based Regimen in Adult Subjects with Newly Diagnosed Nontuberculous Mycobacterial (NTM) Lung Infection Caused by Mycobacterium avium Complex (MAC)
- A Phase 2, Double-Blind, Randomized, Parallel-Group, Placebo-Controlled, Multi-Center Study to Evaluate the Efficacy, Safety, and Tolerability of Oral Omadacycline in Adult Subjects with Nontuberculous Mycobacterial (NTM) Pulmonary Disease Caused by Mycobacterium abscessus Complex (MABc)
- A Randomized, Double-Blinded, Placebo-Controlled, Multicenter, Phase 2, Dose-Ranging Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SPR720 as Compared with Placebo for the Treatment of Patients with Mycobacterium avium Complex (MAC) Pulmonary Disease (SPR720-202)
NTM MAC Clinical Trials – Treatment-Refractory Disease
NTM M. abscessus Clinical Trials
Bronchiectasis Clinical Trials
- Randomized, double-blind, placebo-controlled to evaluate the safety, and efficacy of ARINA-1 administered twice daily by nebulizer in adult participants with non-cystic fibrosis bronchiectasis (NCFBE) with excess mucus and cough
- A Phase 2, Multi-Center, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Safety, Phage Kinetics, and Efficacy of Inhaled AP-PA02 Multi-Phage Therapeutic in Subjects with Non-Cystic Fibrosis Bronchiectasis and Chronic Pulmonary Pseudomonas aeruginosa Infection (AP-PA02)